Immunofluorescence Microscopy to Characterize DNA repair Processes | Protocol Preview

Immunofluorescence Microscopy to Characterize DNA repair Processes | Protocol Preview

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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy - a 2 minute Preview of the Experimental Protocol

Vaibhav Murthy, Dalton Dacus, Monica Gamez, Changkun Hu, Sebastian O. Wendel, Jazmine Snow, Andrew Kahn, Stephen H. Walterhouse, Nicholas A. Wallace
Kansas State University, Division of Biology; University of Bristol, Bristol Medical School, Translational Health Sciences;

Repair of double-strand DNA breaks is a dynamic process, requiring not only formation of repair complexes at the breaks, but also their resolution after the lesion is addressed. Here, we use immunofluorescence microscopy for transient and long-lasting double-stranded breaks as a tool to dissect this genome maintenance mechanism.

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Cancer ResearchDNA repairEducation

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